The Globe

Constantinople

The main Assassin controlled city. Templars a.k.a. the Byzantine Empire, continue the vast struggle to take control of the city. The Ottomans, run by the Sultan, enforce the law, striking both Assassins and Templars if seen doing anything wrong. Assassin Headquarters located here.

Rome

The main power in Italy. The Assassins have recently taken main control over the city (thanks to Ezio Auditore), but their are still small pockets of Templars a.k.a. Borgia.